Article

DTL promotes glycolysis and tumor progression in nasopharyngeal carcinoma cells by degrading KAT2B and activating the PI3K/AKT/mTOR pathway

2025-07-15

Abstract excerpt

<title>Abstract</title> <p>Background Nasopharyngeal carcinoma (NPC) is a prevalent malignancy in East and Southeast Asia, with limited effective treatment options due to late-stage diagnosis. E3 ubiquitin ligase DTL has been implicated in various cancers, but its role in NPC remains obscure. This study aimed to investigate the regulatory mechanisms of DTL in NPC and its potential as a therapeutic target. Methods...

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Literature Corpus work: d6e7e760-6ed4-57b9-bdd8-bf906a3a7cce
DOI: 10.21203/rs.3.rs-7061714/v1

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