Article

NEDD4L-Induced Ubiquitination Mediated UBE2T Degradation Inhibits Progression of Lung Adenocarcinoma Via PI3K-AKT Signaling

2021-10-01

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Accumulating studies have indicated that Ubiquitin-conjugating enzyme E2T (UBE2T), as an oncogene, promotes progression and metastasis of lung cancer, including lung adenocarcinoma (LUAD), but it is completely unknown whether and how UBE2T is ubiquitylated and degraded, and by which E3 ligase. <bold>Methods: </bold>The relationship NEDD4L with UBE2T in LUAD tiss...

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Literature Corpus work: ae55bee5-452f-582e-8e57-c12f89b76f95
DOI: 10.21203/rs.3.rs-948352/v1

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