Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DTL Is a Prognostic Biomarker and Promotes Bladder Cancer Progression through Regulating the AKT/mTOR axis

1 Jan 2022

Abstract excerpt

BACKGROUND: Denticleless E3 ubiquitin protein ligase homolog (DTL) has been reported to be an important regulator for tumorigenesis and progression. Nonetheless, the biological functions and molecular mechanisms of DTL in BCa remain elusive. METHODS: We implemented integrative bioinformatics analysis to explore the diagnostic and prognostic values of DTL based on The Cancer Genome Atlas (TCGA), ArrayExpress, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bladder and Urothelial Cancer Treatments
Share to Epigenetics and DNA Methylation
Share to Ferroptosis and cancer prognosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35103094
DOI: 10.1155/2022/3369858

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DTL Is a Prognostic Biomarker and Promotes Bladder Cancer Progression through Regulating the AKT/mTOR axisPMID 35103094Read ↗

Pan-cancer analysis and experimental validation of DTL as a potential diagnosis, prognosis and immunotherapy biomarkerSemantic proximity Read ↗

MYLK, CNN1, TAGLN and LMOD1 identified as potential prognostic biomarkers for bladder cancer using bioinformatics analysisSemantic proximity Read ↗

RRM2 Is a Putative Biomarker and Promotes Bladder Cancer Progression via PI3K/AKT/mTOR PathwaySemantic proximity Read ↗

Screening and Identification of Key Biomarkers for Bladder Cancer: A Study Based on TCGA and GEO DataSemantic proximity Read ↗

CALD1 promotes the expression of PD-L1 in bladder cancer via the JAK/STAT signaling pathwaySemantic proximity Read ↗

DTL promotes glycolysis and tumor progression in nasopharyngeal carcinoma cells by degrading KAT2B and activating the PI3K/AKT/mTOR pathwaySemantic proximity Read ↗

Identification of Key Biomarkers in Bladder Cancer: Evidence from a Bioinformatics AnalysisSemantic proximity Read ↗

DTL is a novel downstream gene of E2F1 and promotes the progress of hepatocellular carcinomaSemantic proximity Read ↗

NEAT1/MALAT1/XIST/PKD--Hsa-Mir-101-3p--DLGAP5 Axis as a Novel Diagnostic and Prognostic Biomarker Associated With Immune Cell Infiltration in Bladder CancerSemantic proximity Read ↗

CALD1, CNN1, and TAGLN identified as potential prognostic molecular markers of bladder cancer by bioinformatics analysisSemantic proximity Read ↗

Low FBXL7 Expression Indicates Low Overall Survival in Bladder CancerSemantic proximity Read ↗

Ubiquitin-conjugating enzyme E2T (UBE2T) and denticleless protein homolog (DTL) are linked to poor outcome in breast and lung cancersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.