Article

Hypoxia-mediated YTHDF2 expression and activation of the mTOR/AKT axis in lung squamous cell carcinoma

2021-08-02

Abstract excerpt

<title>Abstract</title> <p>Background N6-methyladenosine (m6A) is a dynamic and reversible internal RNA structure of eukaryotic mRNA. YTH domain family 2 (YTHDF2), an m6A-specific reader YTH domain family, plays fundamental roles in several types of cancer. However, the function of YTHDF2 in lung squamous cell carcinoma (LUSC) remains elusive. Methods Functionally, NCI-H226 and SK-MES-1 cells were exposed to hy...

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Literature Corpus work: d52c6435-dee8-5af1-95f2-bf59d31b2c79
DOI: 10.21203/rs.3.rs-694246/v1

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