Article

Distinct oligodendrocyte populations have spatial preference and injury-specific responses

2019-03-18

Abstract excerpt

Oligodendrocytes (OLs), the myelinating cells of the central nervous system, are transcriptionally heterogeneous, 1 the origin and functional consequences of which are unknown. Functional heterogeneity of MOLs might correlate with the local environment or their interactions with different neuron types. 2 Here, we show that distinct MOL populations have spatial preference in the mammalian central nervous system a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d6e620c9-8956-5b34-a930-9868d838ce9d
DOI: 10.1101/580985

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Distinct oligodendrocyte populations have spatial preference and injury-specific responsesDOI 10.1101/580985Read

Human spinal cord organoids recapitulate developmental and disease-associated oligodendrocyte lineage signaturesSemantic proximity Read

Functional heterogeneity of oligodendrocyte progenitor cells in the central nervous systemSemantic proximity Read

Genetically Labeled Premyelinating Oligodendrocytes: Bridging Oligodendrogenesis and Neuronal ActivitySemantic proximity Read

Single-cell Transcriptomics Analyses Revealed Specialized Microglial Subsets with Oligodendrocyte-like SignaturesSemantic proximity Read

Heterogeneity of oligodendrocyte progenitor cells in adult human brainSemantic proximity Read

Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous systemSemantic proximity Read

Diversity of Adult Neural Stem and Progenitor Cells in Physiology and DiseaseSemantic proximity Read

Oligodendrocyte Development and Myelination in Neurodevelopment: Molecular Mechanisms in Health and DiseaseSemantic proximity Read

Disease-specific oligodendrocyte lineage cells arise in multiple sclerosisSemantic proximity Read

Single-cell transcriptomic reveals molecular diversity and developmental heterogeneity of human stem cell-derived oligodendrocyte lineage cells.Semantic proximity Read

Motor System Oligodendroglia Atlas Reveals Activation States Associated with Region-Specific Vulnerability in ALSSemantic proximity Read

Single-Cell Transcriptomic Insights into Conserved and Divergent Oligodendrocyte Lineage Programs Across SpeciesSemantic proximity Read