Article

Genetic predisposition to genomic instability in cancer

1998-01-01

Abstract excerpt

Ataxia telangiectasia and Bloom's syndrome are cancer prone genomic instability disorders for which the causative genes <i>ATM</i> and <i>BLM</i> have only recently been identified. The cellular localisation and biochemical roles of these proteins are currently being defined. ATM shares sequence homology with several lipid and protein kinases but at the outset of this work a kinase function for ATM itself was not...

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Literature Corpus work: d6cf51f5-c6ff-5271-ac15-fcfbf25e717b
DOI: 10.21954/ou.ro.0000fed0

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