Article

The trappin gene family: proteins defined by an N-terminal transglutaminase substrate domain and a C-terminal four-disulphide core

1999-06-15

Abstract excerpt

Recently, several new genes have been discovered in various species which are homologous to the well-characterized human epithelial proteinase inhibitor elafin/SKALP (skin-derived anti-leukoproteinase). Because of the high degree of conservation and the similarities in genomic organization, we propose that these genes belong to a novel gene family. At the protein level, the family members are defined by: (1) an N-...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d6ca863e-7b63-570e-9e0c-4776f034ac6b
DOI: 10.1042/0264-6021:3400569

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The trappin gene family: proteins defined by an N-terminal transglutaminase substrate domain and a C-terminal four-disulphide coreDOI 10.1042/0264-6021:3400569Read

The trappin gene family: proteins defined by an N-terminal transglutaminase substrate domain and a C-terminal four-disulphide coreSemantic proximity Read

Update of the human and mouse SERPIN gene superfamily.Semantic proximity Read

Constitutive and inducible expression of SKALP/elafin provides anti-elastase defense in human epithelia.Semantic proximity Read

Characterisation of an Ovine Keratin Associated Protein (KAP) Gene, Which Would Produce a Protein Rich in Glycine and Tyrosine, but Lacking in Cysteine.Semantic proximity Read

Comparative sequence analyses reveal rapid and divergent evolutionary changes of the WFDC locus in the primate lineage.Semantic proximity Read

Trappin ovine molecule (TOM), the ovine ortholog of elafin, is an acute phase reactant in the lung.Semantic proximity Read

SLPI and elafin: multifunctional antiproteases of the WFDC familySemantic proximity Read

Human clade B serpins (ov-serpins) belong to a cohort of evolutionarily dispersed intracellular proteinase inhibitor clades that protect cells from promiscuous proteolysisSemantic proximity Read

ADAM-TS5, ADAM-TS6, and ADAM-TS7, Novel Members of a New Family of Zinc MetalloproteasesSemantic proximity Read

An Updated Nomenclature for Keratin-Associated Proteins (KAPs)Semantic proximity Read

A novel 25 bp tandem repeat within the human trefoil peptide gene TFF2 in 21q22.3: polymorphism and mammalian evolution.Semantic proximity Read

Tissue-specific expression, functional analysis, and polymorphism of the KRT2 gene in sheep horn.Semantic proximity Read