Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Constitutive and inducible expression of SKALP/elafin provides anti-elastase defense in human epithelia.

15 Sept 1996

Abstract excerpt

Skin-derived antileukoproteinase (SKALP), also known as elafin, is a serine proteinase inhibitor first discovered in keratinocytes from hyperproliferative human epidermis. In addition to the proteinase inhibiting domain which is directed against polymorphonuclear leukocyte (PMN) derived enzymes such as elastase and proteinase 3, SKALP contains multiple transglutaminase (TGase) substrate domains which enable...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood properties and coagulation
Share to Skin and Cellular Biology Research
Share to Wound Healing and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8823304
DOI: 10.1172/jci118926

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Constitutive and inducible expression of SKALP/elafin provides anti-elastase defense in human epithelia.PMID 8823304Read ↗

SKALP/elafin: an elastase inhibitor from cultured human keratinocytes. Purification, cDNA sequence, and evidence for transglutaminase cross-linkingSemantic proximity Read ↗

Expression of SKALP/elafin during wound healing in human skinSemantic proximity Read ↗

Aberrant mucosal wound repair in the absence of secretory leukocyte protease inhibitor.Semantic proximity Read ↗

The trappin gene family: proteins defined by an N-terminal transglutaminase substrate domain and a C-terminal four-disulphide coreSemantic proximity Read ↗

The trappin gene family: proteins defined by an N-terminal transglutaminase substrate domain and a C-terminal four-disulphide coreSemantic proximity Read ↗

Urokinase-type plasminogen activator is a preferred substrate of the human epithelium serine protease tryptase epsilon/PRSS22.Semantic proximity Read ↗

Identification of Lympho-Epithelial Kazal-Type Inhibitor 2 in Human Skin as a Kallikrein-Related Peptidase 5-Specific Protease InhibitorSemantic proximity Read ↗

The antiprotease SPINK7 serves as an inhibitory checkpoint for esophageal epithelial inflammatory responses.Semantic proximity Read ↗

Neutrophil gelatinase‐associated lipocalin is a marker for dysregulated keratinocyte differentiation in human skinSemantic proximity Read ↗

Aberrant human tissue kallikrein levels in the stratum corneum and serum of patients with psoriasis: dependence on phenotype, severity and therapy.Semantic proximity Read ↗

SPINK5 and Netherton syndrome: novel mutations, demonstration of missing LEKTI, and differential expression of transglutaminases.Semantic proximity Read ↗

Molecular cloning of seprase: a serine integral membrane protease from human melanomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.