Trappin ovine molecule (TOM), the ovine ortholog of elafin, is an acute phase reactant in the lung.

Abstract excerpt

As large animal models continue to play an important role in translating lung-directed therapeutic strategies from laboratory animals to humans, there is an increasing interest in the analysis of endogenous regulators of inflammation at both a genomic and a therapeutic level. To this end, we have sought to characterize the ovine ortholog of elafin, an important regulator of inflammation in humans. We have...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Inflammation
• Share to Lipopolysaccharides
• Share to Lung