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Article

A novel 25 bp tandem repeat within the human trefoil peptide gene TFF2 in 21q22.3: polymorphism and mammalian evolution.

European journal of human genetics : EJHG - 1 Jan 2000

Kayademir T, Silva E dos S, Pusch C, Beck S, Machado J C, Gött P

Abstract excerpt

Trefoil peptides belong to a family of small secretory proteins characterised by three intrachain disulfide bonds forming the trefoil motif (TFF-domain). They serve to maintain or repair the epithelial mucosa, and promote cell migration. They are predominantly found in gastrointestinal tissues, and are upregulated around areas of epithelial damage, and in meta- and neoplasia. The corresponding three genes are...

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Source

Identifiers

PMID: 9781055
DOI: 10.1038/sj.ejhg.5200166

Genes

TFF2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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