Article
A novel 25 bp tandem repeat within the human trefoil peptide gene TFF2 in 21q22.3: polymorphism and mammalian evolution.
European journal of human genetics : EJHG - 1 Jan 2000
Kayademir T, Silva E dos S, Pusch C, Beck S, Machado J C, Gött P
Abstract excerpt
Trefoil peptides belong to a family of small secretory proteins characterised by three intrachain disulfide bonds forming the trefoil motif (TFF-domain). They serve to maintain or repair the epithelial mucosa, and promote cell migration. They are predominantly found in gastrointestinal tissues, a...
Topics
- Alleles
- Animals
- Base Sequence
- Biological Evolution
- Chromosomes, Human, Pair 21
- Cloning, Molecular
- DNA
- Gene Frequency
- Growth Substances
- Humans
- Molecular Sequence Data
- Mucins
- Multigene Family
- Muscle Proteins
- Neuropeptides
- Peptides
- Polymerase Chain Reaction
- Polymorphism, Genetic