Article
The ABCG2 resistance network of glioblastoma
2009-09-15
Abstract excerpt
Glioblastoma multiforme (GBM) is the most common and lethal primary brain tumor variant. It exhibits heterogeneity at both the morphologic and genetic levels, with a complex combination of somatic alterations rendering the tumor class difficult to adequately treat. The role of so-called “cancer stem-cells” (CSCs) in the resistance of high-grade gliomas like GBM to conventional treatment regimens has received much...
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Identifiers and source
- Literature Corpus work
- d69ea756-af9c-5cdc-ba69-464610177cf1
- DOI
- 10.4161/cc.8.18.9504