Article

Validation of the new pathology staging system for progressive supranuclear palsy

2021-01-25

Abstract excerpt

Progressive supranuclear palsy (PSP) is a neurodegenerative disorder associated with neuroglial accumulation of 4-repeat tau protein. Kovacs et al. have recently proposed a new semi-quantitative staging system to categorise the severity of PSP pathology, using the distribution of tau aggregates as it progresses from subcortical to cerebellar and cortical regions. Here, we test the new PSP pathology staging system...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7a3393fe-40d3-53e7-8755-97470bf3291d
DOI: 10.1101/2021.01.18.21250017

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Validation of the new pathology staging system for progressive supranuclear palsyDOI 10.1101/2021.01.18.21250017Read

Progressive supranuclear palsy: clinicopathological concepts and diagnostic challenges.Semantic proximity Read

Neuropathological validation of the MDS-PSP criteria with PSP and other frontotemporal lobar degenerationSemantic proximity Read

Clinical, cognitive, and morphometric profiles of progressive supranuclear palsy phenotypes.Semantic proximity Read

Neuropathology of variants of progressive supranuclear palsy.Semantic proximity Read

The diagnosis of progressive supranuclear palsy: current opinions and challenges.Semantic proximity Read

Is the Phenotype Designation by PSP-MDS Criteria Stable Throughout the Disease Course and Consistent With Tau Distribution?Semantic proximity Read

Progressive Supranuclear Palsy: an Update.Semantic proximity Read

Progressive supranuclear palsy: current approach and challenges to diagnosis and treatment.Semantic proximity Read

Data-driven modelling of tau pathology reveals distinct progressive supranuclear palsy subtypesSemantic proximity Read

Latent trait modeling of tau neuropathology in progressive supranuclear palsySemantic proximity Read

Progressive supranuclear palsy: a systematic review.Semantic proximity Read

Progressive supranuclear palsy (PSP): Richardson syndrome and other PSP variants.Semantic proximity Read