Article
Protracted course progressive supranuclear palsy.
European journal of neurology - 1 Aug 2022
Couto Blas, Martinez-Valbuena Ivan, Lee Seojin, Alfradique-Dunham Isabel, Perrin Richard J, Perlmutter Joel S, Cruchaga Carlos, Kim Ain, Visanji Naomi, Sato Christine, Rogaeva Ekaterina, Lang Anthony E, Kovacs Gabor G
Abstract excerpt
BACKGROUND AND PURPOSE: Progressive supranuclear palsy (PSP) encompasses a broader range of disease courses than previously appreciated. The most frequent clinical presentations of PSP are Richardson syndrome (RS) and PSP with a predominant Parkinsonism phenotype (PSP-P). Time to reach gait dependence and cognitive impairment have been proposed as prognostic disease milestones. Genetic polymorphisms in TRIM11 and...
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