Article

The dispensability of 14-3-3 proteins for the regulation of human cardiac sodium channel Na <sub>v</sub> 1.5

2022-10-26

Abstract excerpt

<h4>Background</h4> 14-3-3 proteins are ubiquitous proteins that play a role in cardiac physiology ( e.g ., metabolism, development, and cell cycle). Furthermore, 14-3-3 proteins were proposed to regulate the electrical function of the heart by interacting with several cardiac ion channels, including the voltage-gated sodium channel Na v 1.5. Given the many cardiac arrhythmias associated with Na v 1.5 dysfunct...

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Literature Corpus work: d67bd220-8f96-55f6-b646-b94689951772
DOI: 10.1101/2022.10.26.513875

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