Article
Biology of cardiac sodium channel Nav1.5 expression.
Cardiovascular research - 1 Jan 2012
Rook Martin B, Evers Melvin M, Vos Marc A, Bierhuizen Marti F A
Abstract excerpt
Na(v)1.5, the pore forming α-subunit of the voltage-dependent cardiac Na(+) channel, is an integral membrane protein involved in the initiation and conduction of action potentials. Mutations in the gene-encoding Na(v)1.5, SCN5A, have been associated with a variety of arrhythmic disorders, includi...
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