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An idiosyncratic, zonated stroma encapsulates desmoplastic liver metastases and originates from injured liver

2022-08-24

Abstract excerpt

Colorectal cancer liver metastases (CRLM) grow in two major patterns defined by the histomorphology of the invasion front, replacement or desmoplastic . The desmoplastic pattern, in which a stromal rim separates tumor cells and liver parenchyma is a strong positive prognostic factor, implying favorable biological features. However, the origin of the perimetastatic stroma is unknown and the underlying biological me...

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Literature Corpus work
d65f047e-6460-5321-8698-7b8721b23bb1
DOI
10.1101/2022.08.24.22279162
Open publication

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An idiosyncratic, zonated stroma encapsulates desmoplastic liver metastases and originates from injured liverDOI 10.1101/2022.08.24.22279162
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