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Unveiling the Significance of Arginine, a second shell conserved residue on structure, stability, and activity of Non- Seleno human Peroxiredoxin 6

2025-07-02

Abstract excerpt

<title>Abstract</title> <p>1-Cys Peroxiredoxin 6 (Prdx6) is a unique bifunctional antioxidant enzyme highly expressed in mammalian lungs. It plays a dual role in cancer, acting as both a suppressor and promoter during different stages of tumor development. Prdx6 exhibits two distinct enzymatic activities: phospholipase A2 (PLA2) activity for phospholipid cleavage and peroxidase activity that reduces reactive oxyg...

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Literature Corpus work
d60968d6-eace-5151-a114-ae4da126caf3
DOI
10.21203/rs.3.rs-6831445/v1
Open publication

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Unveiling the Significance of Arginine, a second shell conserved residue on structure, stability, and activity of Non- Seleno human Peroxiredoxin 6DOI 10.21203/rs.3.rs-6831445/v1
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