Article

Identification of an intrinsically disordered region (IDR) in arginyltransferase 1 (ATE1)

2024-08-24

Abstract excerpt

Arginyltransferase 1 (ATE1) catalyzes arginylation, an important post-translational modification (PTM) in eukaryotes that plays a critical role in cellular homeostasis. The disruption of ATE1 function is implicated in mammalian neurodegenerative disorders and cardiovascular maldevelopment, while post-translational arginylation has also been linked to the activities of several important human viruses such as SARS-C...

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Literature Corpus work: 8f4178f1-a531-50a6-aa8f-359217f9dff5
DOI: 10.1101/2024.08.23.609426

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