Article

Investigation of miR-133a, miR-637 and miR-944 genes expression and their relationship with PI3K/AKT signaling in women with breast cancer

2022-10-28

Abstract excerpt

<h4>Background: </h4> MicroRNA (miRNA) is a regulatory molecule capable of positively or negatively regulating signaling pathways and furthermore assumes a part tumorigenesis and various aspects of cancer. The purpose of this study is to investigate the expression level of miR-133a, miR-637 and miR-944 genes in serum and tumor tissue and their relationship with the expression level of phosphatidylinositol-3-kinase...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d5fe099a-2fd6-534a-ae9b-c621b714d5e0
DOI: 10.21203/rs.3.rs-2204784/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Investigation of miR-133a, miR-637 and miR-944 genes expression and their relationship with PI3K/AKT signaling in women with breast cancerDOI 10.21203/rs.3.rs-2204784/v1Read

microRNA-133a regulates the cell cycle and proliferation of breast cancer cells by targeting epidermal growth factor receptor through the EGFR/Akt signaling pathway.Semantic proximity Read

Correlation between activation of PI3K/AKT/mTOR pathway and prognosis of breast cancer in Chinese women.Semantic proximity Read

Evaluation of MiR-1908-3p as a novel serum biomarker for breast cancer and analysis its oncogenic function and target genesSemantic proximity Read

Pan-cancer analysis on the role of PIK3R1 and PIK3R2 in human tumorsSemantic proximity Read

The Correlation of Mutations and Expressions of Genes within the PI3K/Akt/mTOR Pathway in Breast Cancer-A Preliminary Study.Semantic proximity Read

Identification and validation of miR-583 and mir-877-5p as biomarkers in patients with breast cancer: an integrated experimental and bioinformatics researchSemantic proximity Read

LNC01089-LINC00963/miR-1244-5p/IGF1 ceRNA axis might regulate FOXO signaling pathway in breast cancer patients: a biomarker discovery investigationSemantic proximity Read

Long non-coding RNAs as the critical regulators of PI3K/AKT, TGF-β, and MAPK signaling pathways during breast tumor progressionSemantic proximity Read

Phosphoinositide 3-Kinase (PI3K) Inhibitors and Breast Cancer: An Overview of Current AchievementsSemantic proximity Read

In Silico and Experimental Outcomes of the Expression of miR508-5p and miR-635 in Tumor Compared with Non-Tumor Adjacent Tissues of Patients with Breast CancerSemantic proximity Read

Biology and therapeutic potential of PI3K signaling in ER+/HER2-negative breast cancer.Semantic proximity Read

The Effect and Treatment of PIK3CA Mutations in Breast Cancer: Current Understanding and Future DirectionsSemantic proximity Read