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Article

The Correlation of Mutations and Expressions of Genes within the PI3K/Akt/mTOR Pathway in Breast Cancer-A Preliminary Study.

International journal of molecular sciences - 19 Feb 2021

Kołodziej Przemysław, Nicoś Marcin, Krawczyk Paweł A, Bogucki Jacek, Karczmarczyk Agnieszka, Zalewski Daniel, Kubrak Tomasz, Kołodziej Elżbieta, Makuch-Kocka Anna, Madej-Czerwonka Barbara, Płachno Bartosz J, Kocki Janusz, Bogucka-Kocka Anna

Abstract excerpt

There is an urgent need to seek new molecular biomarkers helpful in diagnosing and treating breast cancer. In this elaboration, we performed a molecular analysis of mutations and expression of genes within the PI3K/Akt/mTOR pathway in patients with ductal breast cancer of various malignancy levels. We recognized significant correlations between the expression levels of the studied genes. We also performed a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Phosphatidylinositol 3-Kinases

Share to Proto-Oncogene Proteins c-akt

Share to TOR Serine-Threonine Kinases

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Identifiers

PMID: 33669698
DOI: 10.3390/ijms22042061
PMCID: PMC7922286

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