Article

Association of Ddx5/p68 protein with the upstream erythroid enhancer element (EHS1) of the Klf1 gene

2019-08-22

Abstract excerpt

EKLF/KLF1 is an essential transcription factor that plays a global role in erythroid transcriptional activation. It’s own regulation is of interest, as it displays a highly restricted expression pattern, limited to erythroid cells and its progenitors. Here we use biochemical affinity purification to identify the Ddx5/p68 protein as an activator of KLF1 by virtue of its interaction with the erythroid-specific DNAse...

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Literature Corpus work: d5bfa7d4-5a45-54b2-88cd-7420de38eb01
DOI: 10.1101/743435

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