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Article

Comprehensive characterization of erythroid-specific enhancers in the genomic regions of human Krüppel-like factors

28 Aug 2013

Abstract excerpt

BACKGROUND: Mapping of DNase I hypersensitive sites (DHSs) is a powerful tool to experimentally identify cis-regulatory elements (CREs). Among CREs, enhancers are abundant and predominantly act in driving cell-specific gene expression. Krüppel-like factors (KLFs) are a family of eukaryotic transcription factors. Several KLFs have been demonstrated to play important roles in hematopoiesis. However, transcriptional...

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PMID: 23985037
DOI: 10.1186/1471-2164-14-587

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