Article

Strain-specific changes in nucleus accumbens transcriptome and motivation for food reward in mice exposed to maternal separation

2023-04-06

Abstract excerpt

Adversity in childhood exerts enduring effects on brain and increases the vulnerability to psychiatric diseases. It also leads to a higher risk for eating disorders and obesity. We hypothesised that neonatal stress in mice affects motivation to obtain palatable food in adulthood and changes gene expression in reward system. Male and female pups from C57Bl/6J and C3H/HeN mice strains were subjected to a daily mater...

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Literature Corpus work: d5af4b56-b96d-534b-83ce-e7c136a07571
DOI: 10.1101/2023.04.06.535855

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