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Effects of early-life stress on peripheral and central mitochondria in male mice across ages

29 Jun 2021

Abstract excerpt

Exposure to early-life stress (ES) increases the vulnerability to develop metabolic diseases as well as cognitive dysfunction, but the specific biological underpinning of the ES-induced programming is unknown. Metabolic and cognitive disorders are often comorbid, suggesting possible converging underlying pathways. Mitochondrial dysfunction is implicated in both metabolic diseases and cognitive dysfunction and...

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PMID: 34274734
DOI: 10.1016/j.psyneuen.2021.105346

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