Article

Changes in nano-mechanical properties of human epidermal cornified cells in children with atopic dermatitis

2020-07-17

Abstract excerpt

<h4>Background: </h4> Impaired skin barrier is an important etiological factor in atopic dermatitis (AD). The structural protein filaggrin (FLG) plays a major role in maintenance of the competent skin barrier and its deficiency is associated with enhanced susceptibility to mechanical injury. Here we examined biomechanical characteristics of the corneocytes in children with AD and healthy controls. <h4>Methods: <...

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Literature Corpus work: d59864be-f1a1-5ff7-bf83-c9e5b377e5b7
DOI: 10.12688/wellcomeopenres.15729.2

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