Article

Novel Highly Homeostatic B Cells induced by Immunomodulatory Oligonucleotide IMT504

2025-12-22

Abstract excerpt

<h4>ABSTRACT</h4> Cellular homeostasis depends on endoplasmic reticulum (ER) function and is highly sensitive to ER stress typically triggered by protein-folding overload. To restore balance, eukaryotic cells engage the unfolded protein response (UPR), a network of signaling pathways that enhances resistance to stress by upregulating chaperones, reducing global translation, and promoting degradation of unfolded p...

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Literature Corpus work: d5848426-dc40-5d59-88fe-16bd5f86486f
DOI: 10.64898/2025.12.18.694904

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