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No association between the<i>Plasmodium vivax crt-o</i>MS334 or In9<i>pvcrt</i>polymorphisms and chloroquine failure in a clinical cohort from Malaysia

2022-12-01

Abstract excerpt

Increasing reports of resistance to a frontline malaria blood-stage treatment, chloroquine (CQ), raise concerns for the elimination of Plasmodium vivax . The absence of an effective molecular marker of CQ resistance in P. vivax greatly constrains surveillance of this emerging threat. A recent genetic cross between CQ sensitive (CQS) and CQ resistant (CQR) NIH-1993 strains of P. vivax linked a moderate CQR phenotyp...

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Literature Corpus work
d5838a4c-2cc4-5e2c-a339-cd92f74a6af0
DOI
10.1101/2022.11.30.22282917
Open publication

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