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Article

Plasmodium vivax resistance to chloroquine in Madagascar: clinical efficacy and polymorphisms in pvmdr1 and pvcrt-o genes.

Antimicrobial agents and chemotherapy - 1 Dec 2008

Barnadas Céline, Ratsimbasoa Arsène, Tichit Magali, Bouchier Christiane, Jahevitra Martial, Picot Stéphane, Ménard Didier

Abstract excerpt

No data were available concerning Plasmodium vivax resistance to chloroquine (CQ) in Madagascar. We investigated the therapeutic efficacy of CQ in P. vivax malaria, the prevalence of mutations in the pvcrt-o and pvmdr1 genes before treatment, and the association between mutant parasites and the clinical response of the patients to CQ treatment. Clinical isolates were collected at six sentinel sites located in the...

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Identifiers

PMID: 18809933
DOI: 10.1128/AAC.00578-08
PMCID: PMC2592859

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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