Article
Distribution of Mutations Associated with Antifolate and Chloroquine Resistance among Imported Plasmodium vivax in the State of Qatar.
The American journal of tropical medicine and hygiene - 1 Dec 2017
Bansal Devendra, Acharya Anushree, Bharti Praveen K, Abdelraheem Mohamed H, Elmalik Ashraf, Abosalah Salem, Khan Fahmi Y, ElKhalifa Mohamed, Kaur Hargobinder, Mohapatra Pradyumna K, Sehgal Rakesh, Idris Mohammed A, Mahanta Jagadish, Singh Neeru, Babiker Hamza A, Sultan Ali A
Abstract excerpt
Plasmodium vivax is the most prevalent parasite worldwide, escalating by spread of drug resistance. Currently, in Qatar, chloroquine (CQ) plus primaquine are recommended for the treatment of P. vivax malaria. The present study examined the prevalence of mutations in dihydrofolate reductase (dhfr), dihydropteroate synthase (dhps) genes and CQ resistance transporter (crt-o) genes, associated with...
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