Article

Exploratory spatial peptidomic profiling during incubation of drug seeking following cocaine plus alcohol self-administration in young adult rats

2026-08-07

Abstract excerpt

<h4>Background</h4> Concurrent cocaine and alcohol use is one of the most prevalent forms of polysubstance consumption and is associated with poorer clinical outcomes than cocaine use alone. However, the regional molecular adaptations induced by combined exposure remain poorly understood. Here, we used matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS) to characterize peptide/protei...

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Literature Corpus work: d5578429-ef50-5b71-b040-bed6af469b99
DOI: 10.64898/2026.08.03.742404

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