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Neurobiological Signatures of Alcohol Dependence Revealed by Protein Profiling

16 Dec 2013

Abstract excerpt

Alcohol abuse causes dramatic neuroadaptations in the brain, which contribute to tolerance, dependence, and behavioral modifications. Previous proteomic studies in human alcoholics and animal models have identified candidate alcoholism-related proteins. However, recent evidences suggest that alcohol dependence is caused by changes in co-regulation that are invisible to single protein-based analysis. Here, we...

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PMID: 24358215
DOI: 10.1371/journal.pone.0082656

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