Article

<i>In silico</i> molecular target prediction unveils mebendazole as a potent MAPK14 inhibitor

2020-05-20

Abstract excerpt

The concept of polypharmacology involves the interaction of drug molecules with multiple molecular targets. It provides a unique opportunity for the repurposing of already-approved drugs to target key factors involved in human diseases. Herein, we used an in silico target prediction algorithm to investigate the mechanism of action of mebendazole, an anti-helminthic drug, currently repurposed in the treatment of b...

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Literature Corpus work: d553e04e-efba-5d52-ab64-8cb99bb39774
DOI: 10.1101/2020.05.18.101329

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