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Predicting Anticancer Targets of Mebendazole Through Network Pharmacology: An Integrated Analysis of Molecular Targets, Signalling Pathways, and Clinical Trial Evidence

2026-04-02

Abstract excerpt

<title>Abstract</title> <p>Mebendazole (MBZ), a broad-spectrum anthelmintic benzimidazole with an established safety profile, has attracted significant interest as a candidate for oncological drug repurposing. Despite growing preclinical and early clinical evidence, a systematic characterisation of MBZ's multi-target anticancer mechanisms has not been comprehensively performed. Here, we employed a network pharmac...

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Literature Corpus work
2388f6c0-3025-5294-b990-e6ab6c93c092
DOI
10.21203/rs.3.rs-9198127/v1
Open publication

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Predicting Anticancer Targets of Mebendazole Through Network Pharmacology: An Integrated Analysis of Molecular Targets, Signalling Pathways, and Clinical Trial EvidenceDOI 10.21203/rs.3.rs-9198127/v1
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