Article

eIF6 Promotes Inﬂammatory Macrophage Phenotype, Foam Cell Formation and Atherosclerosise

2021-08-27

Abstract excerpt

<h4>Background: </h4> ： Atherosclerosis is a chronic inflammatory disease, caused by accumulation of lipid-laden and inflammatory macrophages in the artery wall. Understanding its molecular mechanisms and developing novel therapeutic targets to promote atherosclerotic regression is an important clinical goal. <h4>Methods: </h4> ApoE -/- and eIF6 +/- /ApoE -/- mice were fed Western diet (WD) for 16 weeks. Molecular...

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Literature Corpus work: d5453be1-4e84-5c99-bc63-3e7b9338cd4e
DOI: 10.21203/rs.3.rs-820763/v1

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