Article

Expression, purification and characterization of α-synuclein fibrillar specific scFv from inclusion bodies

2020-05-20

Abstract excerpt

<title>Abstract</title> <p>Background: Aggregation of α-synuclein (α-syn) has been implicated in multiple neurodegenerative disorders including Parkinson’s disease (PD), dementia with Lewy bodies (DLB) and multiple system atrophy (MSA), collectively grouped as synucleinopathies. Recently, recombinant antibody fragments (Fab, scFvs and diabodies) against α-syn have emerged as an alternative to the traditional full...

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Literature Corpus work: d52186c2-2651-58d1-929a-729c8fe0debf
DOI: 10.21203/rs.3.rs-29455/v1

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