Article

Corticotropin-releasing hormone stimulates mast cell degranulation and proliferation in human nasal mucosa

2024-01-30

Abstract excerpt

<h4>Background: </h4> Psychological stress exacerbates mast cell (MC)-dependent inflammation, including nasal allergy, but the underlying mechanisms are not well understood. Because the key stress-mediating neurohormone, corticotropin-releasing hormone (CRH), induces human skin MC degranulation, we hypothesized that CRH may be a key player in stress-aggravated nasal allergy. The current study probes this hypothesi...

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Literature Corpus work: d51787bf-e871-5cde-bd62-5f80aa0518ac
DOI: 10.22541/au.170664521.14440057/v1

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