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Article

Corticotropin releasing hormone and the skin.

Frontiers in bioscience : a journal and virtual library - 1 Sept 2006

Slominski Andrzej, Zbytek Blazej, Zmijewski Michal, Slominski Radomir M, Kauser Sobia, Wortsman Jacobo, Tobin Desmond J

Abstract excerpt

Cotricotropin-releasing hormone (CRH) and related peptides are produced in skin that is dependent on species and anatomical location. Local peptide production is regulated by ultraviolet radiation (UVR), glucocorticoids and phase of the hair cycle. The skin also expresses the corresponding receptors (CRH-R1 and CRH-R2), with CRH-R1 being the major receptor in humans. CRH-R1 is expressed in epidermal and dermal...

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Identifiers

PMID: 16720310
DOI: 10.2741/1966
PMCID: PMC1847336

Genes

CRH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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