Article
Alopecia areata and Affected Skin CRH Receptor Upregulation Induced by Acute Emotional Stress
1 Jan 2001
Abstract excerpt
BACKGROUND: Recent evidence indicates that acute stress can precipitate a number of dermatological conditions, including alopecia areata. This effect may be mediated by corticotropin-releasing hormone (CRH) released locally in the skin from dorsal root ganglia or immune cells. CRH typically acts through activation of specific receptors that are either type 1 or types 2 alpha and 2 beta. CRH, or related peptides...
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