Article
Phenotypic characteristics of nasal mast cells in a mouse model of allergic rhinitis.
ORL; journal for oto-rhino-laryngology and its related specialties - 1 Jan 2014
Li Pu, Cui Yeqing, Song Gongru, Wang Zhenlin, Zhang Qiuhang
Abstract excerpt
BACKGROUND: Mast cells (MCs) in the nasal respiratory mucosa (NRM) play a triggering role in the pathogenesis of allergic rhinitis (AR). Recent research evidence in mouse models of AR suggests an underlying MC-related allergic response in mouse nasal olfactory mucosa (NOM). OBJECTIVE: We sought to investigate the phenotypic characteristics of nasal MCs in a mouse model of AR. METHODS: By MC-specific staining and...
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