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Article

Phenotypic characteristics of nasal mast cells in a mouse model of allergic rhinitis.

ORL; journal for oto-rhino-laryngology and its related specialties - 1 Jan 2014

Li Pu, Cui Yeqing, Song Gongru, Wang Zhenlin, Zhang Qiuhang

Abstract excerpt

BACKGROUND: Mast cells (MCs) in the nasal respiratory mucosa (NRM) play a triggering role in the pathogenesis of allergic rhinitis (AR). Recent research evidence in mouse models of AR suggests an underlying MC-related allergic response in mouse nasal olfactory mucosa (NOM). OBJECTIVE: We sought to investigate the phenotypic characteristics of nasal MCs in a mouse model of AR. METHODS: By MC-specific staining and...

Topics

Animals
Carboxypeptidases
Disease Models, Animal
Endopeptidases
Enzyme-Linked Immunosorbent Assay
Eosinophils
Female
Immunoenzyme Techniques
Immunoglobulin E
Mast Cells
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Inbred BALB C

Nasal Mucosa

Phenotype

Rhinitis, Allergic

Source

Identifiers

PMID: 25531303
DOI: 10.1159/000369142

Genes

NRM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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