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Article

Differential Expression of a Cutaneous Corticotropin-Releasing Hormone System

11 Nov 2003

Abstract excerpt

We completed the mapping of a cutaneous CRH signaling system in two species with widely different determinants of skin functions, humans and mice. In human skin, the CRH receptor (CRH-R) 1 was expressed in all major cellular populations of epidermis, dermis, and subcutis with CRH-R1alpha being the most prevalent isoform. The CRH-R2 gene was expressed solely in hair follicle keratinocytes and papilla fibroblasts,...

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Identifiers

PMID: 14605004
DOI: 10.1210/en.2003-0851

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