Article

Characterisation of Two <i>Plasmodium</i> Virulence Factors Important for Lipid Metabolism and Disease Progression <i>In Vivo</i>

2025-12-22

Abstract excerpt

Malaria is caused by Plasmodium parasites and claims 610,000 deaths annually. Parasite invasion of red blood cells (RBCs) involves secretion of multiple proteins from specialised apical organelles (micronemes, rhoptries, and dense granules). These collectively facilitate host cell entry, establish a protective parasitophorous vacuole (PV), and directly and indirectly mediate interactions between the infected RBC...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d7fd36ed-0187-54f7-a890-23e577553b0f
DOI: 10.64898/2025.12.21.695507

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Characterisation of Two <i>Plasmodium</i> Virulence Factors Important for Lipid Metabolism and Disease Progression <i>In Vivo</i>DOI 10.64898/2025.12.21.695507Read

MMV687794 blocks <i>Plasmodium falciparum</i> invasion of red blood cells by targeting a Surface-associated Lipid-Interacting Rhoptry Protein, <i>Pf</i> SLIRPSemantic proximity Read

An essential dual-function complex mediates erythrocyte invasion and channel-mediated nutrient uptake in malaria parasitesSemantic proximity Read

Maurer's clefts, the enigma of <i>Plasmodium falciparum</i>Semantic proximity Read

Iron transport pathways in the human malaria parasite <i>Plasmodium falciparum</i> revealed by RNA-sequencingSemantic proximity Read

Erythrocyte membrane protein 3 (EMAP3) is exposed on the surface of the <i>Plasmodium berghei</i> infected red blood cellSemantic proximity Read

PfCERLI1 is a conserved rhoptry associated protein essential for Plasmodium falciparum merozoite invasion of erythrocytesSemantic proximity Read

A High-Resolution Map of SBP1 Interactomes in Plasmodium falciparum-infected ErythrocytesSemantic proximity Read

Characterization of a Conserved Rhoptry-Associated Leucine Zipper-Like Protein in the Malaria Parasite <i>Plasmodium falciparum</i>Semantic proximity Read

The spatial proteome of the <i>Plasmodium falciparum</i> schizont illuminates the composition and evolutionary trajectories of its organellesSemantic proximity Read

<i>Pfcerli2</i> , a duplicated gene in the malaria parasite <i>Plasmodium falciparum</i> essential for invasion of erythrocytes as revealed by phylogenetic and cell biological analysisSemantic proximity Read

An exported protein-interacting complex involved in the trafficking of virulence determinants in Plasmodium-infected erythrocytesSemantic proximity Read

Exported Proteins Required for Virulence and Rigidity of Plasmodium falciparum-Infected Human ErythrocytesSemantic proximity Read