Article

Brooklyn plots to identify co-expression dysregulation in single cell sequencing

2023-06-24

Abstract excerpt

<h4>ABSTRACT</h4> Altered open chromatin regions, impacting gene expression, is a feature of some human disorders. We discovered it is possible to detect global changes in genomically-related gene co-expression within single cell RNA sequencing (scRNA-seq) data. We built a software package to generate and test non-randomness using ‘Brooklyn plots’ to identify the percent of genes significantly co-expressed from t...

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Literature Corpus work: d4ede2b7-12f4-5558-89a6-1dee0d7ff5ee
DOI: 10.1101/2023.06.21.545951

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