Article

scLink: Inferring Sparse Gene Co-expression Networks from Single-cell Expression Data

2020-09-20

Abstract excerpt

A system-level understanding of the regulation and coordination mechanisms of gene expression is essential to understanding the complexity of biological processes in health and disease. With the rapid development of single-cell RNA sequencing technologies, it is now possible to investigate gene interactions in a cell-type-specific manner. Here we propose the scLink method, which uses statistical network modeling t...

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Literature Corpus work: 20a6e7ee-d33b-5f74-abe2-190a28d16a15
DOI: 10.1101/2020.09.19.304956

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