Article

Dozer: Debiased personalized gene co-expression networks for population-scale scRNA-seq data

2023-04-28

Abstract excerpt

Population-scale single cell RNA-seq (scRNA-seq) datasets create unique opportunities for quantifying expression variation across individuals at the gene co-expression network level. Estimation of co-expression networks is well-established for bulk RNA-seq; however, single-cell measurements pose novel challenges due to technical limitations and noise levels of this technology. Gene-gene correlation estimates from...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 92369581-a659-5d7f-87c2-4ee9aeab4d8d
DOI: 10.1101/2023.04.25.538290

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Dozer: Debiased personalized gene co-expression networks for population-scale scRNA-seq dataDOI 10.1101/2023.04.25.538290Read

Cell-type-specific co-expression inference from single cell RNA-sequencing dataSemantic proximity Read

Leveraging gene correlations in single cell transcriptomic dataSemantic proximity Read

scLink: Inferring Sparse Gene Co-expression Networks from Single-cell Expression DataSemantic proximity Read

Single-Cell Transcriptomics Unveils Gene Regulatory Network PlasticitySemantic proximity Read

Augmenting the human interactome for disease prediction through gene networks inferred from human cell atlasSemantic proximity Read

Single-cell network biology for resolving cellular heterogeneity in human diseases.Semantic proximity Read

A novel graph-based k-partitioning approach improves the detection of gene-gene correlations by single-cell RNA sequencingSemantic proximity Read

MuDCoD: Multi-Subject Community Detection in Personalized Dynamic Gene Networks from Single Cell RNA SequencingSemantic proximity Read

Alignment of single-cell RNA-seq samples without over-correction using kernel density matchingSemantic proximity Read

Joint Gene Network Construction by Single-Cell RNA Sequencing DataSemantic proximity Read

Identification of genetic variants that impact gene co-expression relationships using large-scale single-cell dataSemantic proximity Read

Single-cell interactomes of the human brain reveal cell-type specific convergence of brain disordersSemantic proximity Read