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Mitochondria in early development: linking the microenvironment, metabolism and the epigenome

14 Mar 2019

Abstract excerpt

Mitochondria, originally of bacterial origin, are highly dynamic organelles that have evolved a symbiotic relationship within eukaryotic cells. Mitochondria undergo dynamic, stage-specific restructuring and redistribution during oocyte maturation and preimplantation embryo development, necessary to support key developmental events. Mitochondria also fulfil a wide range of functions beyond ATP synthesis, including...

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PMID: 30870807
DOI: 10.1530/rep-18-0431

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