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Article

The role of GLI1 for 5-Fu resistance in colorectal cancer

13 Apr 2017

Abstract excerpt

Colorectal cancer is a leading cause of cancer-related mortality worldwide, with Fluorouracil (5-FU)-based chemotherapy as the major treatment for advanced disease. Many patients with advanced colorectal cancer eventually succumb to the disease despite some patients responded initially to chemotherapy. Thus, identifying molecular mechanisms responsible for chemotherapy resistance will help design novel strategies...

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PMID: 28413604
DOI: 10.1186/s13578-017-0145-7

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