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Mechanisms and Strategies to Overcome Drug Resistance in Colorectal Cancer

25 Feb 2025

Abstract excerpt

Colorectal cancer (CRC) is a major cause of cancer-related mortality worldwide, with a significant impact on public health. Current treatment options include surgery, chemotherapy, radiotherapy, molecular-targeted therapy, and immunotherapy. Despite advancements in these therapeutic modalities, resistance remains a significant challenge, often leading to treatment failure, poor progression-free survival, and...

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PMID: 40076613
DOI: 10.3390/ijms26051988

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