Article
RNAse-free manufacture of Venezuelan Equine Encephalitis Virus (VEEV) plasmid DNA vaccine
2025-05-23
Abstract excerpt
The long shelf-life and stability of DNA makes this platform highly attractive for low-cost, rapid delivery of pandemic response vaccines. Protocols utilized for clinical grade plasmid manufacture by contract development and manufacturing organizations are not readily accessible to academic and public research laboratories engaged in early-phase plasmid vaccine development. We present here the framework for DNA ma...
Topics
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- Bacteriophages and microbial interactions
- CAR-T cell therapy research
- CRISPR and Genetic Engineering
- Protein purification and stability
- Viral gastroenteritis research and epidemiology
- Viral Infections and Outbreaks Research
- Viral Infectious Diseases and Gene Expression in Insects
- Virus-based gene therapy research
Identifiers and source
- Literature Corpus work
- d493b032-bcd6-5799-8906-19f3727410d6
- DOI
- 10.1101/2025.05.22.655656
