Article

Evaluation of Vibrio natriegens as a fast-growing alternative host for plasmid DNA production

2026-03-16

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Plasmid DNA (pDNA) is a key biomolecule for gene therapies, DNA vaccines, and mRNA-based applications. Although <italic>Escherichia coli</italic> is the established host for pDNA production, limitations such as moderate growth rates and endotoxin-associated challenges motivate the exploration of alternative production hosts. <italic>Vibrio natriegens</itali...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 126d00cf-c39d-5768-8f2a-cab96770e75b
DOI: 10.21203/rs.3.rs-9108382/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Evaluation of Vibrio natriegens as a fast-growing alternative host for plasmid DNA productionDOI 10.21203/rs.3.rs-9108382/v1Read

Outpacing <i>E. coli</i> : Development of <i>Vibrio natriegens</i> as a Next-Generation Cloning HostSemantic proximity Read

miniVec: A miniaturized plasmid backbone supporting antibiotic-free and additive-free fermentation with enhanced yield and functionalitySemantic proximity Read

Maximization of the Minicircle DNA Vaccine Production Expressing SARS-CoV-2 RBDSemantic proximity Read

Automation workflow for high-throughput arrayed plasmid DNA preparation and quantificationSemantic proximity Read

A simple method to provide a shuttling plasmid for delivery to other host ascertained by prolonged stability of extracellular plasmid DNA released from Escherichia coli K12 endA mutant, deficient in major endonuclease.Semantic proximity Read

Advancing <i>Vibrio</i> genetics: A platform for efficient genomic manipulationSemantic proximity Read

Quantification of Plasmid Copy Number with Single Colour Droplet Digital PCR.Semantic proximity Read

High-efficiency transfection of <i>Acanthamoeba castellanii</i> using a cationic polymerSemantic proximity Read

An <i>E. coli</i> -based platform for the production and assembly of anellovirus vectorsSemantic proximity Read

Enhanced production of plasmid DNA by engineered Escherichia coli strains.Semantic proximity Read

Automated Assembly of Programmable RNA-Based SensorsSemantic proximity Read

A single-plasmid-based, easily curable CRISPR/Cas9 system for rapid, iterative genome editing in Pseudomonas putida KT2440Semantic proximity Read