Article

Purification of plasmid DNA for use in human gene therapy

2001-01-01

Abstract excerpt

Two key issues defined the focus of this research in manufacturing plasmid DNA for use In human gene therapy. First, the processing of E.coli bacterial cells to effect the separation of therapeutic plasmid DNA from cellular debris and adventitious material. Second, the affinity purification of the plasmid DNA in a Simple one-stage process. The need arises when considering the concerns that have been recently voice...

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Literature Corpus work: bb37c73c-4584-5a20-bfc5-b933c5a3d28c
DOI: 10.48780/publications.aston.ac.uk.00009632

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